Lacto Therapeutics skin technology is rooted in the groundbreaking advancements of lactoferrin research

Lactoferrin, the new skin beauty formulation

Lactoferrin, a unique immunity-boosting ingredient, plays a vital role in the lives of mammals, including humans. This essential immune component, known for its natural pink hue, is present in colostrum and amniotic fluid. It can also be found in bodily secretions like tears and nasal mucosa, where it serves as a shield against external irritants.

Notably abundant in the first milk or colostrum it protects newborns with low immunity, helping them resist illness. Despite its importance, lactoferrin remains an incredibly rare ingredient, amounting to just 0.2g per liter of milk.

Additionally, lactoferrin is present in the amniotic fluid that safeguards a developing fetus, highlighting its role in nurturing and protecting the skin even before birth. As we age, our skin continues to long for the gentle touch of lactoferrin, craving its protective and revitalizing benefits.While it's commonly believed that large amounts of collagen can enhance skin elasticity or firmness, this alone is not sufficient. Without an adequate balance of elastin, the skin's elasticity cannot be properly maintained.

Elastin plays a crucial role in complementing collagen by tightening the skin's fibers, ensuring that the desired elasticity is achieved. For collagen to effectively improve skin quality, elastin is indispensable as the backbone of this delicate balance.

iFormulated with care to protect your skin, Lacto Therapeutics excludes all additives that could cause harm. It contains no synthetic coloring, synthetic fragrances, parabens, alcohol, or petroleum-based surfactants. With a commitment to purity, this natural formula is crafted using only natural yeast and essential oils to ensure gentle and effective skincare.

Lactoferrin: A groundbreaking formulation inspired by extensive skin research

Through years of dedicated experimentation and rigorous verification, we have perfected a unique lactoferrin formulation that enhances the tightness, elasticity, hydration, and radiance of your skin. By overcoming challenges such as heat sensitivity and degradation, we successfully developed a highly concentrated lactoferrin solution to unlock your skin's true beauty.

Our advanced capsule technology enhances penetration capabilities, ensuring that skin beautifying ingredients are effectively delivered to every layer for comprehensive care

Enhanced penetration achieved through the addition of 100% plant-derived ingredients sourced from natural yeast. Our innovative penetrating capsules encase lactoferrin along with other cosmetic components, delivering them deep into the skin to amplify hydration and moisture benefits.

A powerful blend of three micro-osmotic moisturizing components works together to deeply hydrate the skin, delivering lasting moisture and revitalization from within

Cosmetic ingredients often struggle to penetrate deeply into the skin. However, with the use of micro-osmotic moisturizing components such as 'Collagen,' 'Hyaluronic Acid,' and 'Elastin,' we can restore skin elasticity from within, rejuvenating its structure and vitality. 

A blend of water-soluble collagen offers exceptional moisturizing benefits! Known for its ability to retain moisture, water-soluble collagen is ideal for keeping your skin hydrated and refreshed. By carefully dissolving it at low temperatures, its delicate helical structure remains intact, ensuring maximum hydration and effectiveness.

Our advanced capsule technology enhances penetration capabilities, ensuring that skin beautifying ingredients are effectively delivered to every layer for comprehensive care

Enhanced penetration achieved through the addition of 100% plant-derived ingredients sourced from natural yeast. Our innovative penetrating capsules encase lactoferrin along with other cosmetic components, delivering them deep into the skin to amplify hydration and moisture benefits

This innovative formulation delivers twice the effectiveness of Vitamin C in addressing sun-related skin damage. Even in small quantities, it performs comparably to Tranexamic Acid, setting new benchmarks in skincare solutions. When applied to melanin-producing cells, lactoferrin effectively suppresses melanin production, surpassing the beauty-enhancing effects of vitamin C. Melanocytes contain a factor called MITF, which regulates melanin production. As MITF levels rise, melanin production increases. Lactoferrin inhibits the generation of MITF, thereby reducing melanin synthesis. Furthermore, experiments using three-dimensional cultured skin closely mimicking human skin demonstrated that lactoferrin at a 0.5% concentration exhibits melanogenesis-inhibitory effects equivalent to a 2% effective concentration of tranexamic acid—a widely recognized beauty ingredient. This research confirms that cosmetics containing lactoferrin deliver potent anti-aging benefits comparable to leading skin-beautification products, proving its exceptional efficacy

A gel enriched with lactoferrin has been shown to reduce wrinkles by an impressive average of 40%, showcasing its powerful skin-rejuvenating properties

Maintaining youthful, wrinkle-free skin relies heavily on the activity of fibroblasts, which produce essential components like hyaluronic acid. However, factors such as ultraviolet rays and cellular damage can compromise fibroblasts, leading to denatured collagen and elastin, reduced moisture, and the appearance of wrinkles and sagging. Lactoferrin addresses this by reactivating dormant fibroblasts within the skin, restoring firmness and elasticity while visibly reducing wrinkles. A study demonstrated remarkable results after one month of applying a gel with 0.5% lactoferrin twice daily, their skin's moisture levels improved, and wrinkles diminished by an average of 40%. These findings highlight the powerful anti-aging properties of lactoferrin-containing gels as a transformative skincare solution

The effect of lactoferrin on skin was simulated using a recombinant human epidermal model. The anti-inflammatory and soothing effect of lactoferrin was verified using IL-1α and TSLP Elisa assay. The effects of lactoferrin on the expression of related genes and proteins were detected using qPCR and immunofluorescence staining. The results showed that lactoferrin can effectively enhance the Transepidermal Electrical Resistance (TEER) and inhibit the secretion of inflammatory cytokine IL-1α and TSLP. In addition, it was confirmed using qPCR that lactoferrin had high expression levels on AQP3, FLG, IVL, CLDN1 and HAS1 genes. Immunofluorescence staining confirmed that lactoferrin had high fluorescence intensity and expression in AQP3, Filaggrin and Involucrin. The results showed that lactoferrin improved the skin barrier at higher than 1.5 mg/mL. At the same time, it can have anti-inflammatory and moisturizing effects. This study provides a strong basis for the application of lactoferrin in cosmetics and daily chemical products.

https://doi.org/10.3390/cosmetics11030098